Pharmaceutical Giant Pfizer Forced To Shut Down Updated COVID Vaccine Trials

Dr. Marty Makary’s new standards expose the lack of demand for mRNA shots

My how the tables have turned. 

It wasn't long ago that Pfizer was viewed and praised as the savior of humanity. Including by their own CEO, Albert Bourla. Just four and a half years ago, governments, politicians, educational institutions and corporations mandated that employees, students, or even those simply entering offices or facilities receive COVID vaccines.

These policies were created with the help of experts who treated Pfizer's every word as inarguable law. Despite the pharmaceutical giant sharing spurious conclusions about the efficacy of its vaccine, such as claiming it was "100% effective" in preventing COVID-19 cases. Potential side effects were dismissed, the obvious lack of risk to younger age groups was ignored, downplayed, or outright lied about, and the lack of evidence about infection or transmission was covered up.

Instead of an honest discussion, it became good guys vs. bad guys. Good guys support science and COVID vaccines, bad guys don't. Even more frustrating, as it became clear that Pfizer had wildly oversold its products, that not only was there nowhere near 100% efficacy in preventing COVID cases, but that reality was much closer to 0%, experts and politicians dug their heels in. 

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Then the rapid spread of the Omicron variant effectively ended the pandemic, as everyone, vaccinated, masked and boosted or not, got COVID in a matter of months. And it seems like years of making unjustified claims have finally come back to bite them.

Pfizer Halts Latest COVID Vaccine Trial

Reuters reported this week that Pfizer and partner BioN Tech have stopped a "large U.S. trial of their updated COVID-19 vaccine in healthy adults aged 50 to 64."

Why? In part, because there were too few people interested in enrolling to create enough data to find conclusions about efficacy. Essentially, nobody wanted to sign up for the trial, because after years of misleading information, a substantial majority of people have finally realized that the promises of yearly updated COVID-19 vaccines is completely unnecessary for healthy, low-risk individuals.

Pfizer reportedly sent a letter out to trial investigators this week revealing that they would "stop surveillance for signs of COVID illness for all participants in the study after April 3." 

There's little question that this is a result of health officials in the second Trump administration demanding a higher standard of evidence to approve COVID vaccines. The FDA, under new head Dr. Marty Makaray, specifically required larger trials in the 50-64 age group, as well as placebo controls, for any updated COVID shots. That meant Pfizer needed to enroll 25,000-30,000 participants, a target that they were unable to reach, per Reuters.

"This study is not ending as a result of any safety or benefit-risk concerns. We intend to stop the study due to slow enrollment and therefore the inability ​to generate relevant post-marketing data," said Pfizer and BioN Tech in a statement to Reuters.

There are simply not enough healthy people in the 50-64 age group willing to enroll themselves in a trial for COVID vaccines, because they've learned that the risk from COVID were made out to be unnecessarily extreme, while the benefits of the mRNA shots were unjustifiably promoted.

Just 18% of Americans got a COVID booster dose for the 2025-2026 respiratory virus season, though these same experts have continued to push for universal uptake. Ironically, years of Anthony Fauci and Bourla working hand in hand seems to have backfired. And now their golden goose is not likely to be available at all for healthy 50-64 year olds in the coming 2026-2027 season. Why? Because nobody wants it. 

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Ian Miller is the author of two books, a USC alumnus and avid Los Angeles Dodgers fan. He spends most of his time golfing, traveling, reading about World War I history, and eating cereal. Email him at ian.miller@outkick.com