NFL Week 4 Opening Lines Featuring 1st London Game And Dolphins-Bills Part I

Sportsbooks release odds for every NFL game the following week prior to Sunday Night Football. This is the last week with two Monday Night Football games. The NFL goes abroad in Week 4 with the annual Jaguars in London game. Week 4's main events are divisional meetings between the Dolphins-Bills and Ravens-Bengals.

Since I play "guess the lines" Sundays to prepare for the upcoming slate, I dig up all the Week 4 spreads including the four teams playing Monday. Below are the opening NFL Week 4 lines as of Monday, Sept. 25 at 7:30 a.m. ET.

NFL Week 4 Lines

Thursday Night Football, 8:15 p.m. ET

Detroit Lions (2-1) at Green Bay Packers (2-1)

NFL London game, Sunday at 9:30 a.m. ET

Atlanta Falcons (2-1) vs. Jacksonville Jaguars (1-2) at Wembley Stadium

NFL Sunday 1 p.m. ET window (9 games)

Cincinnati Bengals (0-2)* at Tennessee Titans (1-2)

Cincy still has to play its Week 3 Monday Night Football game vs. the Los Angeles Rams.

Washington Commanders (2-1) at Philadelphia Eagles (2-0)*

Tampa Bay Buccaneers (2-0)* at New Orleans Saints (2-1)

The Bucs still have to play its Week 3 Monday Night Football game vs. the Philadelphia Eagles.

Los Angeles Rams (1-1)* at Indianapolis Colts (1-2)

The Rams still need to play their Monday Night Football Week 3 game against the Cincinnati Bengals.

Pittsburgh Steelers (2-1) at Houston Texans (1-2)

Baltimore Ravens (2-1) at Cleveland Browns (2-1)

Denver Broncos (0-3) at Chicago Bears (0-3)

Minnesota Vikings (0-3) at Carolina Panthers (0-3)

Miami Dolphins (3-0) at Buffalo Bills (2-1)

NFL Sunday 4 p.m. ET window (3 games)

Las Vegas Raiders (1-2) at Los Angeles Chargers (1-2)

New England Patriots (1-2) at Dallas Cowboys (2-1)

Arizona Cardinals (1-2) at San Francisco 49ers (3-0)

Sunday Night Football, 8:20 p.m. ET

Kansas City Chiefs (2-1) at New York Jets (1-2)

Monday Night Football, 8:15 p.m. ET

Seattle Seahawks (2-1) at New York Giants (1-2)

Follow or fade my picks here, for not just the NFL but the NBA, NHL, PGA Tour, college football, and college hoops as well!

Written by
Geoff Clark serves as OutKick’s sports betting guru. As a writer and host of OutKick Bets with Geoff Clark, he dives deep into the sports betting landscape and welcomes an array of sports betting personalities on his show to handicap America’s biggest sporting events. Previously, Clark was a writer/podcaster for USA TODAY's Sportsbook Wire website, handicapping all the major sports tentpoles with a major focus on the NFL, NBA and MLB. Clark graduated from St. John University.