College Football Week 7 Opening Odds

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The Michigan State Spartans have covered the spread in each of their last seven games against the rival Michigan Wolverines, but they're 0-6 against the spread so far this season and 7-point betting underdogs on the road at Michigan in this week's opening college football odds at sportsbooks monitored by

The Alabama Crimson Tide have also had issues covering the spread lately, as they're 1-4 ATS in their last five games. Alabama opened as a 3-point road favorite for this week against Texas A&M, which has covered the spread in just two of its last eight home games.

Top-ranked Ohio State opened as a 17.5-point home favorite against Penn State for Week 7 at the sportsbooks, while Notre Dame opened as a 3-point home favorite against USC. Stanford opened as a 5-point home favorite against UCLA with those Pac-12 schools meeting on Thursday night. The Cardinal are 7-0 SU and 6-1 ATS in their last seven games against the Bruins.

Florida State opened as a 9-point home favorite against Louisville, and Baylor an 18-point home favorite against West Virginia on the opening Week 7 betting lines.  LSU opened as a 6.5-point home favorite against Florida, with the Tigers posting marks of 4-1 both SU and ATS in their last five games against the Gators.

Check out the rest of the opening college football odds for the week. For live odds and matchup reports on every game every day, head over to the college football betting section.

Arkansas State at South Alabama +6 TUE

Auburn at Kentucky +1 THU

Western Kentucky at North Texas +26.5 THU

UCLA at Stanford -5 THU

Cincinnati at BYU -7 FRI

Boise State at Utah State +8.5 FRI

Houston at Tulane +16 FRI

UNLV at Fresno State EVEN FRI

UCF at Temple -18

Florida Intl at Middle Tennessee -7

Oregon State at Washington State -8

Texas Tech at Kansas +27

Arizona at Colorado +7

Ole Miss at Memphis +10.5

Louisiana Tech at Mississippi State -15.5

Louisville at Florida State -9

West Virginia at Baylor -18

Iowa at Northwestern +2.5

Purdue at Wisconsin -20.5

Marshall at Florida Atlantic +6.5

South Florida at Connecticut -1.5

Tulsa at East Carolina -11

Western Michigan at Ohio -4

Eastern Michigan at Toledo -28

Pittsburgh at Georgia Tech -3

Buffalo at Central Michigan -7

Northern Illinois at Miami-Ohio +15.5

Akron at Bowling Green -11.5

Georgia State at Ball State -16.5

Kent State at Massachusetts -5

Air Force at Colorado State EVEN

Idaho at Troy -12.5

Virginia Tech at Miami -7

Alabama at Texas A&M +3

Syracuse at Virginia -8.5

Charlotte at Old Dominion -9.5

Oklahoma at Kansas State +4

Michigan State at Michigan -7

Nebraska at Minnesota +1.5

Vanderbilt at South Carolina -7

Nevada at Wyoming +7

New Mexico State at Georgia Southern -26

Appalachian State at Louisiana Monroe +8.5

Hawaii at New Mexico -3.5

Florida at LSU -6.5

Wake Forest at North Carolina -14

Boston College at Clemson -15.5

TCU at Iowa State +18

Texas San Antonio at Southern Mississippi -7.5

USC at Notre Dame -3

Missouri at Georgia -17

Penn State at Ohio State -17.5

Arizona State at Utah -6.5

Oregon at Washington EVEN

San Diego State at San Jose State -2

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Clay Travis is the founder of the fastest growing national multimedia platform, OutKick, that produces and distributes engaging content across sports and pop culture to millions of fans across the country. OutKick was created by Travis in 2011 and sold to the Fox Corporation in 2021. One of the most electrifying and outspoken personalities in the industry, Travis hosts OutKick The Show where he provides his unfiltered opinion on the most compelling headlines throughout sports, culture, and politics. He also makes regular appearances on FOX News Media as a contributor providing analysis on a variety of subjects ranging from sports news to the cultural landscape. Throughout the college football season, Travis is on Big Noon Kickoff for Fox Sports breaking down the game and the latest storylines. Additionally, Travis serves as a co-host of The Clay Travis and Buck Sexton Show, a three-hour conservative radio talk program syndicated across Premiere Networks radio stations nationwide. Previously, he launched OutKick The Coverage on Fox Sports Radio that included interviews and listener interactions and was on Fox Sports Bet for four years. Additionally, Travis started an iHeartRadio Original Podcast called Wins & Losses that featured in-depth conversations with the biggest names in sports. Travis is a graduate of George Washington University as well as Vanderbilt Law School. Based in Nashville, he is the author of Dixieland Delight, On Rocky Top, and Republicans Buy Sneakers Too.