NCAA Tournament 2023 Opening Betting Lines

March Madness, aka the greatest betting event on the sports calendar, tips off Tuesday with the First Four of the NCAA Tournament 2023 and the Round of 64 Thursday, March 16.

For sports bettors, March Madness is pretty much Christmas. Family and work duties get put on hold because there is wall-to-wall action from Thursday a.m. to Sunday p.m.

Our friends at DraftKings Sportsbook released odds for several NCAA Tournament 2023 games with the exception of one "First Four" game and the teams awaiting the winners of those games.

NCAA Tournament 2023: First Four in Dayton, Ohio

Tuesday, March 14th

South Region: 16-seed Southeast Missouri State vs. 16-seed Texas A&M-Corpus Christi

Midwest Region: 11-seed Pittsburgh vs. 11-seed Mississippi State

Wednesday, March 15th

East Region: 16-seed Texas Southern vs. 16-seed Fairleigh Dickinson

West Region: 11-seed Nevada vs. 11-seed Arizona State


NCAA Tournament 2023: Round of 64

Thursday, March 16th

Midwest Region in Kansas City, Missouri

1-seed Houston vs. 16-seed Northern Kentucky

8-seed Iowa vs. 9-seed Auburn

7-seed Texas A&M vs. 10-seed Penn State

2-seed Texas vs. 15-seed Colgate


South Region in Louisville, Kentucky

1-seed Alabama vs. 16-seed TBD

8-seed Maryland vs. 9-seed West Virginia

5-seed San Diego State vs. 12-seed Charleston

4-seed Virginia vs. 13-seed Furman

7-seed Missouri vs. 10-seed Utah State

2-seed Arizona vs. 15-seed Princeton


East Region in New York, NY

5-seed Duke vs. 12-seed Oral Roberts

4-seed Tennessee vs. 13-seed Louisiana-Lafayette

West Region in Las Vegas

1-seed Kansas vs. 16-seed Howard

8-seed Arkansas vs. 9-seed Illinois

7-seed Northwestern vs. 9-seed Boise State

2-seed UCLA vs. 15-seed UNC Asheville


Friday, March 17th

Midwest Region

5-seed Miami (Florida) vs. 12-seed Drake

4-seed Indiana vs. 13-seed Kent State

3-seed Xavier vs. 14-seed Kennesaw State

6-seed Iowa State vs. 11-seed TBD


South Region

6-seed Creighton vs. 11-seed NC State

3-seed Baylor vs. 14-seed UC Santa Barbara


East Region

1-seed Purdue vs. 16-seed TBD

8-seed Memphis vs. 9-seed Florida Atlantic

6-seed Kentucky vs. 11-seed Providence

3-seed Kansas State vs. 14-seed Montana State

7-seed Michigan State vs. 10-seed Southern California

2-seed Marquette vs. 15-seed Vermont


West Region

5-seed Saint Mary's vs. 12-seed VCU

3-seed Gonzaga vs. 14-seed Grand Canyon

4-seed UConn vs. 13-seed Iona

6-seed TCU vs. 11-seed TBD