College Football Week 13 Opening Odds

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Special to Outkick The Coverage from OddsShark.com

Looking to keep their chances of making the College Football Playoff alive, the Notre Dame Fighting Irish are listed as a 2-point road favorite on the opening Week 13 betting lines for their matchup with the Stanford Cardinal. Notre Dame sits at 10-1 straight up and 7-4 against the spread on the season and at No. 4 in the updated AP Top 25, while Stanford is 9-2 SU and 8-3 ATS and down at No. 13 in that poll. The Cardinal lost 17-14 on the road at Notre Dame when the schools met last season, in the fifth straight UNDER result for totals bettors between the teams dating back to 2010.

Top-ranked Clemson also opened as a road favorite for this week, with the Tigers giving 15.5 points to South Carolina as they try to remain undefeated on the season. Ohio State, no longer undefeated after losing to Michigan State, opened as a 2.5-point road favorite against Michigan. As well, Oklahoma opened as a 3.5-point road favorite against Oklahoma State.

Alabama will visit Auburn for their annual Iron Bowl matchup this week, with the Crimson Tide opening as 13-point favorites and at No. 2 in the updated AP Top 25. The Iowa Hawkeyes, a perfect 11-0 SU on the season and 6-5 ATS, will face Nebraska on the road on Friday night in a game that opened as a pick'em at the sportsbooks.

Check out the opening college football odds for the week below. For live odds and matchup reports on every game every day, head over to the OddsShark.com college football betting section.

Bowling Green at Ball State +20.5 (TUE)

Ohio at Northern Illinois -13.5 (TUE)

South Florida at UCF OFF (THU)

Texas Tech at Texas -2 (THU)

Miami at Pittsburgh -6 (FRI)

Marshall at Western Kentucky -10.5 (FRI)

Navy at Houston -1.5 (FRI)

Western Michigan at Toledo -9.5 (FRI)

Kent State at Akron -9 (FRI)

Eastern Michigan at Central Michigan -23 (FRI)

Troy at Georgia State -1 (FRI)

Missouri at Arkansas -14 (FRI)

Oregon State at Oregon -30 (FRI)

Washington State at Washington OFF (FRI)

Iowa at Nebraska EVEN (FRI)

Boise State at San Jose State +10 (FRI)

Massachusetts at Buffalo -6 (FRI)

Baylor at TCU EVEN (FRI)

Tulsa at Tulane +3 (FRI)

UCLA at USC -3.5

Colorado at Utah -15.5

Notre Dame at Stanford +2

North Carolina at NC State +6

Virginia Tech at Virginia +3.5

Alabama at Auburn +13

Georgia at Georgia Tech +4.5

Oklahoma at Oklahoma State +3.5

Wisconsin at Minnesota +2.5

Indiana at Purdue +5

Maryland at Rutgers +2

Southern Mississippi at Louisiana Tech -6.5

Iowa State at West Virginia -13.5

Ohio State at Michigan +2.5

Florida Atlantic at Old Dominion +5.5

Louisville at Kentucky +4

Clemson at South Carolina +15.5

Cincinnati at East Carolina +3

SMU at Memphis -24.5

Boston College at Syracuse +4.5

Duke at Wake Forest +4

Louisiana Lafayette at Appalachian State -20.5

UNLV at Wyoming OFF

South Alabama at Georgia Southern -21

Middle Tennessee at Texas San Antonio +11

Charlotte at Rice -9.5

Penn State at Michigan State OFF

Northwestern at Illinois +3.5

UTEP at North Texas -4

BYU at Utah State +2

Arkansas State at New Mexico State +17

Vanderbilt at Tennessee -17.5

Kansas State at Kansas +21.5

Texas State at Idaho EVEN

Connecticut at Temple -12.5

Ole Miss at Mississippi State +2

Texas A&M at LSU -4

Florida State at Florida -3

Colorado State at Fresno State +8.5

Arizona State at California -3

Air Force at New Mexico +10.5

Nevada at San Diego State -14

Louisiana Monroe at Hawaii OFF

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Clay Travis is the founder of the fastest growing national multimedia platform, OutKick, that produces and distributes engaging content across sports and pop culture to millions of fans across the country. OutKick was created by Travis in 2011 and sold to the Fox Corporation in 2021. One of the most electrifying and outspoken personalities in the industry, Travis hosts OutKick The Show where he provides his unfiltered opinion on the most compelling headlines throughout sports, culture, and politics. He also makes regular appearances on FOX News Media as a contributor providing analysis on a variety of subjects ranging from sports news to the cultural landscape. Throughout the college football season, Travis is on Big Noon Kickoff for Fox Sports breaking down the game and the latest storylines. Additionally, Travis serves as a co-host of The Clay Travis and Buck Sexton Show, a three-hour conservative radio talk program syndicated across Premiere Networks radio stations nationwide. Previously, he launched OutKick The Coverage on Fox Sports Radio that included interviews and listener interactions and was on Fox Sports Bet for four years. Additionally, Travis started an iHeartRadio Original Podcast called Wins & Losses that featured in-depth conversations with the biggest names in sports. Travis is a graduate of George Washington University as well as Vanderbilt Law School. Based in Nashville, he is the author of Dixieland Delight, On Rocky Top, and Republicans Buy Sneakers Too.